Tue 4 Oct 2011
A Vitamin of a Different Sort
Question: Estimate the number of people you expect to die in the United States from the following causes over the course of the following year:
1. Homicides _____ or Suicides _____
2. Floods _____ or Tuberculosis _____
3. Tornadoes ____ or Asthma ______
If you’re like most people you will rate the number of deaths from homicides, floods and tornadoes as being higher than suicides, tuberculosis and asthma, but this is wrong. In fact, the numbers for the latter have been consistently higher than each of the former since records have been kept.
The above test, courtesy of unlearning101.com, is a vitamin of a different sort. It should serve as something of an antidote, or vaccination, an inoculation against all the misleading information out there, particularly on the internet, but beyond that web as well, on vitamins, diet and nutrition, and not only those related subjects but information in the health field in general.
Nothing New
Vitamins, as vitamins, as they are known these days, are relatively new to the scene, at least in the grand scheme of things. They have their origins around the turn of the last century and since then have become a major health trend and resource. Still the idea of vitamins is perhaps nothing new, that there are factors in our diet, beyond food as we normally think of food, important to our health, without which we will suffer in some way from their deficiencies.
Stark
William Stark was a pioneer, a reckless pioneer, but a pioneer nonetheless. A physician and friend of Benjamin Franklin, and Sir John Pringle, he decided to use himself as a guinea pig in a series of experiments relating to nutrition. Perhaps a comment by Franklin that concerned his living on bread and water for two weeks suggested the experiments.
He began a series of 24 experiments, to investigate scurvy as well as the benefits of proper nutrition, and lived on bread and water, with a little sugar, for 31 days. He became ‘dull & listless’ with this regimen, spent some time recovering from his first experiment, and continued the series, adding one food at a time.
He added, among other things, olive oil, milk, and roast goose; two months of this and his gums were bleeding with pressure applied, a symptom of scurvy.
He died in February of 1770, considering fruits and vegetables, but continuing tests with honey pudding and Cheshire cheese. Scurvy, if not the cause of death, was plainly contributory and his legacy pointed to the importance of Vitamin C in the diet.
(More in Wikipedia here and here.)
Nyktalopia
Nyktalopia, or night blindness, is mentioned by Hippocrates. The Egyptians are said to have had a cure in the form of powdered liver. Night blindness is the result of a Vitamin A deficiency. The identification of this factor in the liver, that it was indeed Vitamin A, took place around the time of World War I. The Egyptians, though they had never identified the factor itself, were still aware of the link.
(More here.)
Casimir Funk
There are 13 known vitamins. There are no good vitamins or bad vitamins; they all have a role to play in our metabolism. Most of them cannot be manufactured by the body, vitamins D & K are the exceptions, so must be ingested through our diet in some way or else. Prior to the identification of these substances it was a hit or miss thing. Nowadays we have more alternatives. The so-called third world doesn’t have the luxuries available to the ‘developed’ nations and the deficiencies we are talking about can still present as major problems.
Vitamins are normally categorized as fat or water soluble. Vitamins A, D, E, and K are the former and all the eight B vitamins and C the latter. The body stores fat-soluble vitamins for longer periods of time. The water-soluble variety (B12 is something of an exception) must be replenished more often.
Casimir Funk coined the term ‘vitamine’, from vital and amine, for amine of life. At the time, in 1912, it was thought the organic micro-nutrient food factors preventing beriberi and similar deficiency conditions brought about by diet might be chemical amines. Of course this has sense proved not to be the case and ‘vitamine’ was shortened to vitamin.
In short a vitamin is a nutrient essential to health, but required by the organism in only small amounts, and without which the organism will eventually die.
High Seas
Another trend that brought the subject closer to hand, historically speaking, was the advent of long ocean voyages during the Renaissance. Without access to fresh fruits and vegetables for prolonged periods the illnesses that might result from vitamin deficiencies became common on ship’s crews.
James Lind, a British Navy physician, in 1753 published his Treatise on the Scurvy, a summary of a controlled clinical nutrition study of the disease. The Treatise recommended using lemons and limes to prevent scurvy, a strategy that was eventually adopted by the British Royal Navy.
Commenting on the results Lind had said:
… it is indeed not probable, that a remedy for the scurvy will ever be discovered, from a preconceived hypothesis; or by speculative men in the closet, who have never seen the disease, or…. at most, only a few cases of it.
(More here.)
A Skewed Perspective
The most strident viewpoints about vitamins divide them into two groups, so-called natural vitamins, and the synthetic variety. The natural versions of these vitamins are supposed to include additional substances the ‘vitamin’ needs to support its full use by the body. This encompasses the idea that true vitamins are not single substances but complexes. Without the support of these additional substances the vitamin’s effect is rendered less effective, perhaps even neutralized.
Synthetic vitamins, the bare essentials of the vitamin, from this angle are useless. Your body will not incorporate them in the same way as their so-called natural cousins. Just as the viewpoint about natural vitamins is not the whole truth this also is a half-truth.
The bottom line to this argument is really very simple. There is no substitute for a good diet! Vitamins are solutions to deficiencies when they exist but are not going to, by themselves, bring you everything you need.
The question and thrust of optimizing health from a micronutrient and macronutrient stand point needs to focus more on food distribution, safety, and quality rather than on non food supplementation.
(See wandering primate here for some intelligent observations.)
Of course a well-balanced diet should, ideally, include all vitamins needed so supplements, in the forms of vitamins or minerals, are not something your body would need if your diet was perfectly designed.
Of course there is the rub; even if we have the perfect diet following that diet will still be our prerogative. There is still the question as to amount; would a larger dose of vitamins increase their effectiveness in some way? If we were getting from our diet what we needed would more be better?
Fat-soluble vitamins are kept in the body longer and taking them in excess can result in side-effects. For example an excess in Vitamin A can bring about nausea, headache, dry itchy skin in children, weight loss, sometimes diarrhea in adults. An excess of water-soluble vitamins is less risky and side-effects from them practically nil.
(See here.)
In short most of the dialogue re vitamins is skewed, if not beside the point. The focus should never be on supplements in the first place but what constitutes a proper diet. What constitutes a proper diet is the more basic question.
The Future of Vitamins
Jack Uldrich, a futurist, makes a point about Lind and his study, and the eventual adoption by the British Navy of a program to eradicate the disease:
A variety of factors were at work but prominent officials and the sailors alike had different ideas for the best way to prevent scurvy and these erroneous ideas prevented them from being receptive to new knowledge. In short, before they could fully assimilate the new information they first had to unlearn their old knowledge.
(His post is here.)
Really it is similar erroneous ideas, the counter-productive division of natural vs. synthetic being but one of these ideas, that characterize the entire discourse on vitamins, on-line and elsewhere.
Our so-called knowledge is sometimes our greatest enemy, when it is based on assumption and attitude, as opposed to experience and wisdom.















